Vertex Pharmaceuticals Incorporated
VRTX · Healthcare · · USDFahodi Score BUY Long-term (Investment)
72
/ 100
Technical
100
Trend & RS
79
Momentum
79
Fundamental
78
Macro
22
Liquidity
79
| Component | Score | Weight |
|---|---|---|
| Technical | 100.0 | 10% |
| Trend & RS | 78.7 | 10% |
| Momentum | 78.9 | 5% |
| Fundamental | 77.8 | 40% |
| Macro | 22.5 | 15% |
| Liquidity | 79.1 | 20% |
Trade Setup
| Entry | 542.50 |
| Stop Loss | 507.48 (6.5%) |
| Target 1 (1:1) | 577.52 (+6.5%) |
| Target 2 (2:1) | 612.54 (+12.9%) |
| ATR(14) | 17.51 (3.2%) |
| Risk per Share | 35.02 |
| Reward:Risk | 2:1 |
ATR-based levels. Adjust for support/resistance zones.
Factor Profile
| Factor | Score | Z | Bar |
|---|---|---|---|
| Value | 34.8 | -0.61 | |
| Momentum | 71.8 | +0.87 | |
| Quality | 65.2 | +0.61 | |
| Composite | 57.2 | ||
Quality Scores
Piotroski F-Score
7
/9 —
Strong
✓
✓
✗
✗
✓
✓
✓
✓
✓
1. Positive Net Income
2. Positive Roa
3. Positive Cfo
4. Quality Earnings
5. Lower Leverage
6. Higher Liquidity
7. No Dilution
8. Higher Gross Margin
9. Higher Asset Turnover
Altman Z-Score
Insufficient Data
Valuation vs Peers Overvalued
| Metric | Stock | Sector | vs Peers |
|---|---|---|---|
| P/E Ratio | 34.9 | 22.0 | +59% above |
| P/B Ratio | 6.6 | 4.0 | Above |
| Dividend Yield | 0.0% | 1.5% | Below avg |
Comparing against Healthcare median multiples.
Trading at a premium to sector peers — verify growth justifies premium.
Intrinsic Value (DCF) Significantly Overvalued
Intrinsic Value
289.67
vs
Market Price
542.50
Upside
-46.6%
| Margin of Safety | -87.3% |
| Stage 1 PV (5yr FCF) | 17,016,834,431 |
| Terminal Value PV | 56,424,866,369 |
| Total Enterprise Value | 73,441,700,800 |
Assumptions
| Base FCF | 3,151,980,358 |
| Growth Rate (5yr) | 11.8% |
| Terminal Growth | 2.5% |
| Discount Rate (WACC) | 9.0% |
2-stage DCF: 5yr projected FCF + Gordon Growth terminal value. Estimates only — adjust growth and WACC for your own assumptions.
Position Sizing — Kelly Criterion
4.6%
Recommended Size
46.99%
Full Kelly
23.5%
Half Kelly
5.0%
Max Cap (Moderate)
Kelly inputs derived from quant score 72/100. Estimated win rate 62%, avg win 9.3%, avg loss 3.6%. Position was capped at the moderate risk maximum. This is analytical output, not a recommendation to trade.
RECOVERY
Regime: RECOVERY (40% confidence) — position size reduced 8%
Signal Summary STRONG BUY
4
Bullish Signals
0
Bearish Signals
56.45
RSI(14)
8.4863
MACD
Relative Strength (RS) NEUTRAL
71
/ 99
RS Rating
O'Neil filter: <80
| RS vs SPY | → FLAT (+14.3% vs SPY 3M) |
| RS vs Sector | UNDERPERFORMING (Healthcare) |
| RS New High | ✓ RS at 3-month high Institutional accumulation signal |
| Sector Outperformance | -3.6% (3M) |
RS Line — stock / SPY (90 bars)
← older
newer →
RS vs SPY
50-day SMA of RS
NEUTRAL:
In line with the market — no strong outperformance or underperformance.
Technical Indicators
| Indicator | Value | Signal |
|---|---|---|
| Rsi | 56.45 | NEUTRAL |
| Macd | 8.4863 | BULLISH |
| Ma Cross | 522.81 / 481.17 | GOLDEN CROSS |
| Trend Short | ABOVE SMA50 | |
| Trend Long | ABOVE SMA200 | |
| Bollinger | MIDDLE | |
| Volume | 1.47x | NORMAL |
Key Levels
| Level | Price |
|---|---|
| 52-Week High | 568.67 |
| Bollinger Upper | 562.44 |
| SMA(200) | 481.17 |
| SMA(50) | 522.81 |
| SMA(20) | 522.6 |
| Current Price | 542.50 |
| Bollinger Lower | 482.76 |
| 52-Week Low | 406.67 |
| ATR(14) | 17.51 |
Advanced Technical Analysis
Click to expand
Wyckoff Phase & Volume Spread Analysis
Wyckoff Phase
DISTRIBUTION C
Confidence
100%
Upthrust (potential)
Acc: 0.0 |
Dist: 2.5 |
Markup: 0.0 |
Markdown: 0.0
Volume Spread Analysis (last 5 bars)
| Date | Signal | Vol | Description |
|---|---|---|---|
| 2026-10-30 | Normal | 1.79x | Normal bar — no special VSA pattern |
| 2026-11-02 | Normal | 1.9x | Normal bar — no special VSA pattern |
| 2026-11-03 | Normal | 1.4x | Normal bar — no special VSA pattern |
| 2026-11-04 | Normal | 1.08x | Normal bar — no special VSA pattern |
| 2026-11-05 | Normal | 1.47x | Normal bar — no special VSA pattern |
Ichimoku Cloud BULLISH
| Line | Value | Status |
|---|---|---|
| Tenkan-sen (9) | 538.94 | Above Kijun |
| Kijun-sen (26) | 526.38 | Base line |
| Senkou A | 532.66 | Leading span A |
| Senkou B | 526.38 | Leading span B |
| Cloud | 526.38 – 532.66 | Bullish (Green) |
| Price vs Cloud | 542.50 | Above Cloud |
| Chikou Span | 506.74 | Bullish |
| Alignment Score | 4/4 | BULLISH |
TTM Squeeze & Divergences
TTM Squeeze
SQUEEZE OFF
No squeeze
Momentum:
BULLISH FADING
BB: 482.76 – 562.44 | KC: 495.74 – 549.47
Divergences (last 60 bars)
No significant divergences detected in the last 60 bars.
Anchored VWAP
VWAP: 475.11
Anchor: 2025-11-07 (52w Low)
ABOVE AVWAP
+14.2%
Heikin-Ashi Trend
WEAKLY BULLISH
Full data via /api/advanced/VRTX
Valuation
| Metric | Value |
|---|---|
| Market Cap | 137.54B |
| P/E (TTM) | 34.91 |
| Forward P/E | N/A |
| P/B | 6.58 |
| EPS | 15.54 |
Financial Health
| Metric | Value |
|---|---|
| Revenue Growth | 11.8% |
| Profit Margin | 30.7% |
| ROE | 20.8% |
| Debt/Equity | 30.99 |
| Current Ratio | 2.34 |
| Dividend Yield | N/A |
| Payout Ratio | N/A |
| Beta | 0.28 |
Trading Data
542.50
Open
542.50
Day High
542.50
Day Low
2.47M
Volume (2.0x avg)
Price Chart (90 Days)
Candlesticks (green=up, red=down)
SMA 20
SMA 50
Bollinger Bands (upper/lower)
Volume (green=buying, red=selling)